Prof. Habibolah Khazaie and his team published a new released paper in the field of sleep disorder.
Functional neuroimaging techniques have accelerated progress in the study of sleep disorders. Resting state functional MRI (rs-fMRI) studies is a promising non-invasive tool for better understanding of the pathophysiology of sleep disorders. Recently, a systematic review examines the contribution of rs-fMRI to current understanding of two major sleep disorders, insomnia disorder and obstructive sleep apnoea. The underlying core neural mechanisms and neurocircuitry of both disorders are still matter of some debate in the field. However, it’s tempting to infer that the salience network is involved in hyperarousal and affective symptoms in insomnia, while the posterior default mode network appears to underlie cognitive and depressive symptoms of obstructive sleep apnoea. Taken together, an increasing recognition of the complexity of pathophysiological processes in sleep medicine is driving the move towards more personalized diagnosis and treatment approaches where the rs-fMRI may present as a pivotal future clinical tool.
Neurosci Biobehav Rev. 2017 Mar 23. pii: S0149-7634(16)30713-8. doi: 10.1016/j.neubiorev.2017.03.013